Café Synthetique

Café Synthetique is the monthly meetup for the Cambridge synthetic and engineering biology community with informal talks, discussion and pub snacks. Speakers range from students and group leaders to industry professionals and entrepreneurs.

On Monday 2 June, 6pm we have talks from Wes Robertson, MRC LMB and Sonja Blasche, MRC Toxicology Unit.

Wes Robertson, MRC LMB 'Synthetic genomics for microbiome reprogramming'

Abstract: Total genome synthesis enables us to engineer fundamental systems in biology such as the genetic code. Reengineering the genetic code of the model bacteria E. coli has previously enabled emergent applications in synthetic biology, such as viral resistance and unnatural polymer synthesis. Our lab aims to bring these synthetic biology concepts toward investigating the microbiome, where we're starting to develop tools for gut bacteria genome design and synthesis. In particular, recoded gut bacterial genomes provide an orthogonal approach to address unmet needs for the stability and biosecurity of current gut bacterial models used to study and interrogate the microbiome.

Sonja Blasche, MRC Toxicology Unit   'Potential of the kefir community in research and fermented food applications'

Abstract: Milk kefir represents a fascinating example of a naturally evolved, small to medium-sized microbial community composed of lactic acid bacteria, acetic acid bacteria, and yeasts. Traditionally used to ferment milk through the addition of kefir grains—also known as "kefir mushroom"—this community produces the well-known kefir drink. Beyond its long-standing role in food fermentation, milk kefir stands out for its remarkable stability, resilience, and adaptability. These traits make it an ideal model system for exploring microbial community dynamics and species interactions. In my talk, I will highlight the unique opportunities milk kefir offers not only to advance our understanding of symbiotic ecosystems but also to expand the potential of fermentation processes to novel food substrates beyond dairy.

It would be great to see the community coming together again with free aromi food available! Drinks available to purchase at the bar. We look forward to seeing you at the Panton Arms, Cambridge 6pm-8pm.

Places are limited to 40. Please sign up here with full name and affiliation.

For questions or queries please contact Vicky Reid at vr314@cam.ac.uk