Membrane Protein Conference

This Membrane Protein Conference is open to all researchers interested in membrane proteins, including students with an interest in entering this growing field and researchers developing new technologies for membrane protein analysis. We welcome scientists from around the world to present and discuss the latest developments in membrane structural biology, lipid biophysics, trafficking and cellular functions of membrane zones, as well as technologies for preparing physiologically representative targets, screening tools and a variety of systems to stabilize and solubilize native membrane assemblies.

Schedule

We'll begin with Introductions, questions, tips & tricks, where participants are free to introduce themselves briefly, ask questions or offer advice on methods, share news and job postings.

A series of about 9 short talks (15 minutes each) are followed by Q&A (5 minutes) with breaks for discussions.

Participants are invited to vote for the best talk by a junior scientist thanks to support from Nanosene. We'll also decide the next conference date.

Program

13:45 am CEST - Tips and Tricks session to share practical advice on polymers, nanodiscs, etc.

Session 1: Session 1 chaired by Gestél Kuyler, Co-Founder and CEO, Nanosene

14:00 Philipp Hanisch, Head of Laboratory - Protein Service, Cube Biotech GmbH will discuss his recent bioRxiv paper Membrane Proteins at Scale: Automated Copolymer Nanodisc Purification for Structure and Function

14:20 Jasmin Baron, PhD Student in Medical Physics and Biophysics, University of Graz, who recently published Utilizing native nanodiscs to isolate active TRPC3 channels and expand structural analysis capabilities in Sci Rep.

14:40 Anastasiia Sukalskaia, Postdoctoral Researcher with Raimund Dutzler, U Zurich, who recently published on the interactions between TTYH2 and APOE facilitate endosomal lipid transfer in Nature.

15:00 Break

Session 2 chaired by Barry Bruce, Professor, U Tennessee Knoxville

15:05 Lucie Bergdoll, Researcher, LISM - Laboratoire d'ingénierie des systèmes macromoléculaires, CNRS, Aix-Marseille Université recently published membrane lipid composition modulates the organization of VDAC1, a mitochondrial gatekeeper in Commun. Biol.

15:25 Francesca Marassi, Professor Dept Biophysics, Medical College of Wisconsin who recently published in situ NMR reveals a pH sensor motif in an outer membrane protein that drives bacterial vesicle production in PNAS USA.

15:45 Joseph Iovine, PhD student with Nathan Alder, Dept of Molecular and Cell Biology, U Connecticut, who published on lateral lipid packing governs bilayer solubilization by styrene-maleic acid copolymers: a case study with cardiolipin-containing membranes in bioRxiv

16:05 Break

Session 3 chaired by Tomisin Omotoso, BSc Student, U of Alberta

16:10 Richard K. Hite, PI, Sloan Kettering Institute, who recently published Structural basis of ClC-3 transporter inhibition by TMEM9 and PtdIns(3,5)P2 in Nat Struct Mol Biol. 

16:30 Alyssa Ward, PhD Student with F. Barrera, Dept of Biochemistry & Cellular and Molecular Biology, U Tennessee Knoxville recently published cholesterol promotes the formation of dimers and oligomers of the receptor tyrosine kinase ROR1 on bioRxiv.

16:50 Beining Jin, PhD Student with Matthew Eddy, University of Florida, who recently published the Conformational Equilibria of a Human GPCR Compared between Lipid Vesicles and Aqueous Solutions by Integrative 19F-NMR in JACS. 

17:10 Closing Discussions

Organizers

• Alice Rothnie, Senior Lecturer, School of Biosciences Biosciences Research Group, College of Health and Life Sciences, Aston University
• Barry Bruce, Charles P. Postelle Distinguished Professor, Dept. Microbiology; Dept. Biomolecular and Chemical Eng., University of Knoxville, Tennessee
• Bert Klumperman, South African Research Chair in Advanced Macromolecular Architectures at the Department of Chemistry and Polymer Science at Stellenbosch University
• Frank Sobott, ,Chair in Biomolecular Mass Spectrometry, Faculty of Biomedical Sciences, University of Leeds
• Michael Overduin, Professor, Department of Biochemistry, University of Alberta, Canada
  Tim Dafforn, Professor, School of Biosciences, University of Birmingham
• Naomi Pollock, Lecturer in Biosciences, School of Biosciences, College of Health and Life Sciences, Aston University
  
• Stephen Muench, Lecturer in Membrane Biology, School of Biomedical Sciences, University of Leeds
• Tomas Laursen, Assistant Professor, Section for Plant Biochemsitry, University of Copenhagen
• Youzhong Guo, Professor, Department of Medicinal Chemistry, Virginia Commonwealth University

Supporting Partners

ACS Publications

Anatrace

Aurorium

Creative Biolabs

Cube Biotech

DIMA Biotech

FB Reagents

Fluidic Sciences

Malvern Panalytical

Molscreen

Nanosene

RANE Pharmaceutical

Contact us

Let us know if you would like to get involved, we welcome any organizations that would like to contribute at any level. Sponsors and partners have complimentary passes, as well as a range of benefits.