Membrane Protein Conference

This Membrane Protein Conference is open to all researchers interested in membrane proteins, including students with an interest in entering this growing field and researchers developing new technologies for membrane protein analysis. We welcome scientists from around the world to present and discuss the latest developments in membrane structural biology, lipid biophysics, trafficking and cellular functions of membrane zones, as well as technologies for preparing physiologically representative targets, screening tools and a variety of systems to stabilize and solubilize native membrane assemblies.

Schedule

We'll begin with Introductions, questions, tips & tricks, where participants are free to introduce themselves briefly, ask questions or offer advice on methods, share news and job postings.

A series of 8 short talks (15 minutes each) are followed by Q&A (5 minutes) with breaks for discussions.

13:50 CET Informal opening with introductions and sharing of tips & tricks

Speakers from 14:00 CET:

Bernadette Byrne, Professor in Molecular Membrane Biology, Imperial College London, focusses on eukaryotic membrane protein structure and function, with emphasis on transporters and receptors, and will give a talk on the RAMP Lipid Screen.

Hayarpi Torosyan, Postdoctoral Scholar with Kliment A. Verba and Natalia Jura at the University of California, San Francisco, who recently published Structures of the PI3Kα/KRas complex on lipid bilayers reveal molecular mechanisms of PI3Kα activation.

Meseret Haile, PhD Student with Chi-Min Ho, Assistant Professor of Microbiology & Immunology at Columbia University, and recently published structural basis for host membrane binding and remodeling by invading malaria parasites.

Alexej Kedrov, Associate Professor, University of Düsseldorf on the substrate-induced assembly and functional mechanism of the bacterial membrane protein insertase SecYEG-YidC using nanodiscs and cryo-EM.

Surbhi Dhingra, Postdoctoral Fellow with Kenton Swartz, National Institute of Neurological Disorders and Stroke, NIH, who recently published Mechanisms of ligand recognition and channel opening for P2X2 receptors in lipid nanodiscs.

George Hedger, Senior Postdoc with Sarah Rouse, Department of Life Sciences, Imperial College London, on native mass spectrometry, multiscale simulations, machine learning, and fluorescence microscopy of GPCR targets; recently published Ligand-like lipid interactions with membrane proteins: Simulations and machine learning.

Moitrayee Bhattacharyya, Assistant Professor of Pharmacology, Department of Pharmacology, School of Medicine, Yale University, on Single molecule microscopy and cryo-EM with native nanodiscs in understanding neurodegeneration and pain.

Shiv K. Sah Teli, Postdoc­toral Re­searcher with Juha Huiskonen, Laboratory of Structural Biology, University of Helsinki, who published Gating Mechanism of the Human Connexin 45 Gap Junction.

Salma Dienta Salsabila, PhD Student with Jungwook Kim, Gwangju Institute of Science and Technology, who published Structural mechanism of membrane-associated cytidine diphosphate diacylglycerol diphosphatase in Escherichia coli.

Participants are invited to vote for the best talk by a junior scientist thanks to support from Nanosene. We'll also decide the next webconference date.

17:00 Discussion and close

Organizers

• Alice Rothnie, Senior Lecturer, School of Biosciences Biosciences Research Group, College of Health and Life Sciences, Aston University
• Barry Bruce, Charles P. Postelle Distinguished Professor, Dept. Microbiology; Dept. Biomolecular and Chemical Eng., University of Knoxville, Tennessee
• Bert Klumperman, South African Research Chair in Advanced Macromolecular Architectures at the Department of Chemistry and Polymer Science at Stellenbosch University
• Frank Sobott, ,Chair in Biomolecular Mass Spectrometry, Faculty of Biomedical Sciences, University of Leeds
• Michael Overduin, Professor, Department of Biochemistry, University of Alberta, Canada
  Tim Dafforn, Professor, School of Biosciences, University of Birmingham
• Naomi Pollock, Lecturer in Biosciences, School of Biosciences, College of Health and Life Sciences, Aston University
  
• Stephen Muench, Lecturer in Membrane Biology, School of Biomedical Sciences, University of Leeds
• Tomas Laursen, Assistant Professor, Section for Plant Biochemsitry, University of Copenhagen
• Youzhong Guo, Professor, Department of Medicinal Chemistry, Virginia Commonwealth University

Supporting Partners

Creative Biolabs

Fluidic Sciences

Molscreen

Nanosene

RANE Pharmaceutical

Contact us

Let us know if you would like to get involved, we welcome any organizations that would like to contribute at any level. Sponsors and partners have complimentary passes, as well as a range of benefits.